San Francisco

N of 1 Medicine

When access
is not enough.

A retained physician-scientist relationship for care that requires unusual depth, continuity, and judgment.

The relationship

Room for ten. Attention to one.

The practice is limited to ten patients. Population evidence informs care; it does not define an individual.

01 / Assemble

Start with the whole picture.

Bring your history, priorities, and experience into view.

02 / Interpret

Find what matters.

Understand the pattern—and what better would mean for you.

03 / Hypothesize

Make a considered choice.

Decide what to try, what to watch, and when to review.

04 / Measure

Attend to the response.

What actually happens may differ from what was expected.

05 / Revise

Keep the aim. Revise the expectation.

Keep what we have learned. Reconsider what comes next.

Who

For people whose care cannot be understood in fragments.

Many moving parts

Care involves several specialists, a long medical history, or decisions that depend on seeing the whole picture rather than one problem at a time.

A consequential decision

A diagnosis, treatment choice, or change in health calls for careful review, additional perspective, and a physician who can stay with the question.

Prevention that requires judgment

The goal is not simply more testing, but a strategy connecting risk, evidence, personal priorities, and response over time.

Sustained stewardship

One physician holds the context, coordinates the work, and helps the plan evolve.

The retained relationship

Physician time for the work between appointments.

A relationship shaped around the patient. Dedicated physician time, coordination, and continuity, with scope matched to complexity and need.

Dedicated physician capacity

An annual reserve of physician time, within and beyond the consultation.

Deep record review, research, advocacy, referrals, and correspondence

Room for consequential decisions that cannot be compressed into a routine visit

Direct communication and after-hours support

Secure, direct channels and response expectations matched to the clinical situation.

Direct, secure communication with Dr. Sanger

After-hours phone access, with trusted physician backup

Specialist coordination and advocacy

One physician retains the whole picture while outside expertise is brought in deliberately.

Dr. Sanger can join key specialist conversations when useful

Thoughtful scheduling and preparation around important consultations

Recommendations reconciled across specialists and institutions

An extended clinical team

The retained relationship includes practical support for nutrition, movement, medication, and recovery.

A vetted team is brought in around the patient’s priorities rather than as disconnected services

Dr. Sanger retains the medical through-line

Longitudinal diagnostics

Testing selected to answer a question. Findings followed over time.

Measurements interpreted in the context of history, goals, and changing response

New information is incorporated into an evolving plan

Biomedical informatics, in practice

A rare background, used with restraint.

Biomedical informatics is part of Dr. Sanger’s medical craft, not a product layered on top of it. Computational methods extend the field of view across records, evidence, and change over time. Interpretation and care remain physician-led.

Make the record legible

Reconcile records, imaging, laboratory results, and specialist notes into a legible whole, with each finding connected to its source.

Search beyond the obvious

Retrieve and compare guidelines, trials, specialist perspectives, and emerging literature against the patient’s actual eligibility, risks, and goals.

Surface gaps and contradictions

Flag conflicts, missing measurements, assumptions, and unresolved questions for deliberate physician review.

Follow trajectories

Relate interventions to subsequent symptoms, function, biomarkers, and clinical events so the plan can learn from response over time.

Portrait of Patrick Sanger, MD, PhD

The physician

Patrick Sanger, MD, PhD

Dr. Sanger trained at Yale University, earned his MD/PhD in biomedical informatics from the University of Washington, and completed residency in primary care internal medicine at the University of California, San Francisco. Before entering private practice, he practiced primary care at Palo Alto Medical Foundation. He is board certified in Internal Medicine and Clinical Informatics, and has advanced training in clinical lipidology. He serves as Chief Longevity Doctor for PeakHealth AI.

Slow medicine, in rigorous conversation with emerging evidence and technology. A coherent strategy shaped around one patient’s history, priorities, and response.

Board-certified, Internal MedicineBoard-certified, Clinical InformaticsMD/PhD, Biomedical Informatics — University of WashingtonNIH Translational Science FellowshipPrimary Care Internal Medicine Residency — UCSFChief Longevity Doctor — PeakHealth AI

N of 1 Medicine

One physician.Ten patients.Starting at $45,000 per year.

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N of 1 Medicine

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